![Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs | Clinical Epigenetics | Full Text Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs | Clinical Epigenetics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13148-020-00955-w/MediaObjects/13148_2020_955_Figa_HTML.png)
Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs | Clinical Epigenetics | Full Text
![PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells | Nature Structural & Molecular Biology PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells | Nature Structural & Molecular Biology](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fnsmb.2700/MediaObjects/41594_2013_Article_BFnsmb2700_Fig5_HTML.jpg)
PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells | Nature Structural & Molecular Biology
![Distinct PRC2 subunits regulate maintenance and establishment of Polycomb repression during differentiation - ScienceDirect Distinct PRC2 subunits regulate maintenance and establishment of Polycomb repression during differentiation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1097276521002331-fx1.jpg)
Distinct PRC2 subunits regulate maintenance and establishment of Polycomb repression during differentiation - ScienceDirect
![Plants | Free Full-Text | Dynamics of H3K27me3 Modification on Plant Adaptation to Environmental Cues Plants | Free Full-Text | Dynamics of H3K27me3 Modification on Plant Adaptation to Environmental Cues](https://pub.mdpi-res.com/plants/plants-10-01165/article_deploy/html/images/plants-10-01165-g001.png?1623157753)
Plants | Free Full-Text | Dynamics of H3K27me3 Modification on Plant Adaptation to Environmental Cues
Small Molecule Approaches for Targeting the Polycomb Repressive Complex 2 ( PRC2) in Cancer | Journal of Medicinal Chemistry
![IJMS | Free Full-Text | No Easy Way Out for EZH2: Its Pleiotropic, Noncanonical Effects on Gene Regulation and Cellular Function IJMS | Free Full-Text | No Easy Way Out for EZH2: Its Pleiotropic, Noncanonical Effects on Gene Regulation and Cellular Function](https://pub.mdpi-res.com/ijms/ijms-21-09501/article_deploy/html/images/ijms-21-09501-g001.png?1607951360)
IJMS | Free Full-Text | No Easy Way Out for EZH2: Its Pleiotropic, Noncanonical Effects on Gene Regulation and Cellular Function
![Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma | Science Advances Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma | Science Advances](https://www.science.org/cms/10.1126/sciadv.aau5935/asset/809417a0-a44d-49dc-b394-bbd3e1d778cc/assets/graphic/aau5935-f1.jpeg)
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma | Science Advances
![Frontiers | PRC2, Chromatin Regulation, and Human Disease: Insights From Molecular Structure and Function Frontiers | PRC2, Chromatin Regulation, and Human Disease: Insights From Molecular Structure and Function](https://www.frontiersin.org/files/Articles/894585/fonc-12-894585-HTML-r1/image_m/fonc-12-894585-g001.jpg)
Frontiers | PRC2, Chromatin Regulation, and Human Disease: Insights From Molecular Structure and Function
![Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction | Journal of Medicinal Chemistry Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/acs.jmedchem.0c02261/asset/images/large/jm0c02261_0012.jpeg)
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction | Journal of Medicinal Chemistry
![a In wild-type cells, PRC2 complex is recruited to target genes and... | Download Scientific Diagram a In wild-type cells, PRC2 complex is recruited to target genes and... | Download Scientific Diagram](https://www.researchgate.net/publication/343701681/figure/fig1/AS:962096959336452@1606393198198/a-In-wild-type-cells-PRC2-complex-is-recruited-to-target-genes-and-catalyzes-the.png)
a In wild-type cells, PRC2 complex is recruited to target genes and... | Download Scientific Diagram
![PRC2: an epigenetic multiprotein complex with a key role in the development of rhabdomyosarcoma carcinogenesis | Clinical Epigenetics | Full Text PRC2: an epigenetic multiprotein complex with a key role in the development of rhabdomyosarcoma carcinogenesis | Clinical Epigenetics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13148-021-01147-w/MediaObjects/13148_2021_1147_Fig2_HTML.png)
PRC2: an epigenetic multiprotein complex with a key role in the development of rhabdomyosarcoma carcinogenesis | Clinical Epigenetics | Full Text
![Maintaining cell identity: PRC2-mediated regulation of transcription and cancer | Nature Reviews Cancer Maintaining cell identity: PRC2-mediated regulation of transcription and cancer | Nature Reviews Cancer](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fnrc.2016.83/MediaObjects/41568_2016_Article_BFnrc201683_Fig1_HTML.jpg)
Maintaining cell identity: PRC2-mediated regulation of transcription and cancer | Nature Reviews Cancer
![Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric Constraints and Impact of the Regulatory Subunit JARID2 | Journal of the American Chemical Society Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric Constraints and Impact of the Regulatory Subunit JARID2 | Journal of the American Chemical Society](https://pubs.acs.org/cms/10.1021/jacs.9b02321/asset/images/large/ja9b02321_0006.jpeg)